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Precision Therapy

Hormone therapy is a cancer treatment that works by blocking or lowering certain hormones in the body to slow or stop the growth of hormone-sensitive tumors.

Introduction

Precision therapy, also called precision medicine or personalized oncology, is an advanced approach to cancer treatment that customizes therapy for each patient based on the genetic profile of their tumor, molecular markers, and individual health factors.

Not all cancers behave the same way, even if they appear similar under the microscope. Precision therapy allows oncologists to select treatments that target the specific mutations or pathways driving a patient’s cancer. In India, precision oncology is rapidly growing, offering patients more effective, tailored, and safer treatment options.

How Precision Therapy Works?

Precision therapy works by first analyzing the cancer at a molecular level:

  • Genetic testing: Tumor samples are sequenced to identify mutations, biomarkers, or protein expressions.

  • Treatment selection: Based on results, patients may receive targeted therapy, immunotherapy, or specific chemotherapy regimens.

  • Continuous monitoring: Therapy can be adjusted if the cancer changes or develops resistance.

This approach ensures each patient receives the most effective treatment for their unique cancer biology.

How Precision Therapy is Given?

  • Oral targeted drugs or IV infusions depending on therapy type.

  • Treatment duration varies; may continue for months or years based on response.

    • May be combined with chemotherapy, immunotherapy, or radiation for better outcomes.

Goals of Precision Therapy

  • Select the most effective treatment: Use genetic and molecular information to choose drugs that are likely to work.

  • Minimize unnecessary side effects: Avoid therapies unlikely to benefit the patient.

  • Control or shrink tumors: Tailor treatment to block cancer-specific pathways.

  • Support long-term management: Adjust therapy if cancer evolves or becomes resistant.

    • Integrate personalized care: Align with the broader concept of precision medicine for individualized treatment.

Side Effects of Precision Therapy

  • Fatigue or weakness

  • Skin reactions or rashes

  • Diarrhea or nausea

  • Liver or kidney function changes

  • Blood count abnormalities

Side effects vary depending on therapy type and can usually be managed with early intervention.

Life During Precision Therapy – What Patients Should Know

  • Testing first: Molecular profiling is essential to determine which therapy is right.

  • Treatment adherence: Take medications exactly as prescribed; skipping doses can reduce effectiveness.

  • Side effects: Can vary depending on the drug used — may include fatigue, rash, diarrhea, or liver changes.

  • Monitoring: Regular scans and blood tests track response and detect new mutations.

  • Lifestyle: Balanced diet, exercise, and stress management support therapy effectiveness.

  • Emotional well-being: Personalized treatment can feel complex; counseling and support groups help.

When to Contact Your Doctor During Precision Therapy

Contact your doctor promptly if you notice:

  • Severe or persistent side effects (rash, diarrhea, nausea)

  • Yellowing of skin or eyes (possible liver involvement)

  • Unusual bleeding or bruising

  • Sudden fatigue or weakness affecting daily activities

  • New or worsening symptoms during treatment

Timely reporting ensures safety and allows treatment adjustments.

Advances in Precision Therapy

  • Next-generation sequencing (NGS): Detects multiple mutations at once for personalized treatment selection.

  • Biomarker-driven therapy: Drugs are matched to specific genetic or protein markers.

  • Combination approaches: Precision therapy is combined with targeted therapy, immunotherapy, or chemotherapy to improve outcomes.

  • Real-time monitoring: Liquid biopsies track tumor DNA in blood to detect resistance or recurrence early.

  • Broader availability in India: Advanced cancer centers, including in Uttar Pradesh, now provide molecular testing and precision-based treatment plans.

FAQs About Precision Therapy

Q1. Is precision therapy available in India?
Yes, leading cancer centers, including in Uttar Pradesh, now offer molecular profiling and precision medicine.

Q2. Does every patient need genetic testing?
Not always. It is most helpful in advanced cancers or cases where specific mutations can guide treatment.

Q3. Is precision therapy the same as targeted therapy?
Targeted therapy is a part of precision medicine. Precision therapy can include targeted drugs, immunotherapy, or even personalized chemotherapy based on molecular profiling.

Q4. Can precision therapy cure cancer?
It may not cure all cancers, but it can improve outcomes, control tumor growth, and in some cases, achieve long-term remission.

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Dr. Abhishek Tiwari

Medical & Hemato Oncologist

MBBS, MD, DM, ECMO (Europe)

Excellence in cancer care comes from experience, innovation, and compassion. Dr. Abhishek Tiwari, a leading Medical Oncologist in India, offers advanced cancer treatments such as immunotherapy, targeted therapy, precision oncology, etc. With a strong record of guiding patients through their cancer journey with expert care and empathy, Dr. Tiwari is recognized among the best oncologists in India dedicated to delivering effective and personalized treatment.

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